Drug

Overview

This page provides comprehensive pharmacogenomic information about drugs, including genetic variants that influence drug response, efficacy, and adverse reactions. Drug information is sourced from PharmGKB and other pharmacogenomic databases.

Drug Properties

This table displays basic properties and classifications for this drug.

Column	Description
Generic Name	Generic name of the drug
Brand Names	Commercial brand names
Drug Class	Therapeutic classification
Mechanism of Action	Primary mechanism of drug action
Indication	Primary therapeutic indications
Route of Administration	Method of drug delivery
Source	Source of drug information

Associated Variants

This table shows genetic variants associated with this drug from PharmGKB, including information about drug response and pharmacogenomics.

Column	Description
Variant (rsID)	Reference SNP ID of the associated variant (click for variant details)
Gene Symbols	Genes associated with the drug-variant interaction
PMID	PubMed ID supporting the association (click to view publication)
Phenotype Categories	Categories of phenotypic effects or drug responses
Source	Source of the drug-variant association data (click for source details)

Drug-Gene Interactions

This table shows genes that influence this drug’s pharmacokinetics or pharmacodynamics.

Column	Description
Gene	Gene symbol (click for gene details)
Interaction Type	Type of drug-gene interaction (metabolism, transport, target)
Effect	Effect on drug response (increased/decreased efficacy, toxicity)
Evidence Level	Level of evidence for the interaction
Population Frequency	Frequency of relevant variants in major populations
Clinical Annotation	Clinical recommendations based on genotype
Source	Source of the interaction data

Dosing Guidelines

This table provides genotype-based dosing recommendations from clinical pharmacogenomics guidelines.

Column	Description
Gene	Gene affecting drug response
Genotype	Relevant genotype or phenotype
Recommendation	Dosing recommendation
Rationale	Scientific rationale for the recommendation
Population	Population group for the guideline
Guideline Source	Organization providing the guideline (CPIC, DPWG, etc.)
Evidence Level	Strength of evidence supporting the recommendation

Adverse Drug Reactions

This table shows genetic associations with adverse drug reactions for this drug.

Column	Description
Variant	Genetic variant associated with adverse reaction
Adverse Reaction	Type of adverse drug reaction
Risk Level	Relative risk of adverse reaction
Population	Population where association was observed
Evidence Level	Strength of evidence
PMID	Supporting publications
Source	Source of the adverse reaction data

Each table can be sorted by clicking on the column headers. You can also use the search box above each table to filter the results.

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Overview

Drug Properties

Associated Variants

Drug-Gene Interactions

Dosing Guidelines

Adverse Drug Reactions

​Overview

​Drug Properties

​Associated Variants

​Drug-Gene Interactions

​Dosing Guidelines

​Adverse Drug Reactions

Overview

Drug Properties

Associated Variants

Drug-Gene Interactions

Dosing Guidelines

Adverse Drug Reactions